Gut related diseases and the microbiome
Clostridium Difficile
Clostridium difficile and the role of the microbiome
Clostridium difficile is a gram-positive spore forming rod-shaped bacterium. In both humans
and animals C. difficile can be found
in the intestinal tracts. An infection with Clostridium difficile can occur after a disturbance of the normal flora in the colon, due to antibiotics or other disruptive factors.
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Faeces a cure?
At this moment, the current treatment of Clostridium difficile is the antibiotic drug Vancomycin. The only problem with this drug is the low efficacy of it, resulting in a re-infection. Faeces transplantation as alternative is a promising therapy for curing of C. difficile.
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Ulcerative Colitis
Fecal transplantation in ulcerative colitis
Ulcerative colitis is an inflammatory disease that causes diarrhea, bloody stool and abdominal pain. Fecal microbiota transplantations might be able to be a new cure in this discomforting illness.
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